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基础原料

Ion Channel/Membrane Transporter

结构式 货号 产品名称 CAS号
NS1738 结构式
BCP46794 NS1738 501684-93-1
NS1738 is a α7 positive allosteric modulator.
CE-224535 结构式
BCP46785 CE-224535 724424-43-5
CE-224535 is a Purinergic receptor antagonist originated by Pfizer. Phase-II/III for Rheumatoid arthritis and Phase-II for Osteoarthritis were discontinued.
BTT-266 结构式
BCP46757 BTT-266 BTT-266
BTT-266 is a CaVα1⋅CaVβ antagonist which suppresses neuronal voltage-gated calcium-channel trafficking.
AMP PNP 结构式
BCP46541 AMP PNP 72957-42-7
AMP PNP is a non-hydrolyzable AMP analog.
Nitromazenil 结构式
BCP46523 Nitromazenil 84377-97-9
Nitromazenil is similar to Flumazenil which is an imidazodiazepine that selectively blocks the central effects of classic benzodiazepines.
SR 13800 结构式
BCP46368 SR 13800 227321-12-2
SR 13800 is a cell-permeable inhibitor of monocarboxylate transporter 1 (MCT1).
RY785 结构式
BCP45758 RY785 1393748-80-5
RY785 is a selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 µM) that does not affect Cav2 calcium channels.
Vernakalant hydrochloride 结构式
BCP45728 盐酸维那卡兰 748810-28-8
Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channelwt, Kv1.5 channelI508F, Kv1.5 channelT479A, respectively.
(+)-SJ733 结构式
BCP45645 (+)-SJ733 1424799-20-1
(+)-SJ733 is an inhibitor of plasmodium ATP4, leading to rapid clearance in vivo by inducing physical changes in infected, treated red cells.
MitMAB 结构式
BCP45369 MitMAB 1119-97-7
MitMAB, an organic building block and cationic surfactant, is a dynamin inhibitor that inhibits the GTPase activity of dynamin I (Ki = 940 nM; IC50 = 3.1 μM).
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