所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
- Motilin Receptor
- Glucose Transporter
- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Oxytocin Receptor
- Somatostatin Receptor
- Bradykinin Receptor
- Melanocortin Receptor
- Guanylate Cyclase
- Imidazoline Receptor
- PAR
- Neuropeptide Receptor
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Adenosine Receptor
- Glucagon Receptor
- Prostaglandin Receptor
- GnRH Receptor
- NK Receptor
- Glucocorticoid Receptor
- Leukotriene Receptor
- P2 Receptor
- mAChR
- CGRP Receptor
- GPR
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Vasopressin Receptor
- Smoothened/Smo
- mGluR
- Opioid Receptor
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- CGRP Receptor
- FAAH
- nAChR
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- Mitochondrial Metabolism
- Pyruvate Kinase
- SCD
- ALDH
- Serine Protease
- Neprilysin
- CETP
- FTase
- MLR
- MAGL
- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- Elastase
- NOX
- PAI1
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HCV Protease
- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Cytochrome P450
- Proteasome
- ACC
- Xanthine Oxidase
- Carboxypeptidase
- 11β HSD
- COMT
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Infection
- Inflammation
- Cancer
天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
FXR
结构式 | 货号 | 产品名称 | CAS号 |
---|
![]() |
BCP43200 | Cilofexor Tromethamine 新 | 2253764-93-9 |
Cilofexor is a farnesoid X receptor (FXR) agonist.
|
![]() |
BCP40718 | EDP-305 新 | 1933507-63-1 |
EDP-305 is a novel and potent farnesoid X receptor (FXR) agonist, with no/minimal cross-reactivity to TGR5 or other nuclear receptors.
|
![]() |
BCP07472 | 孕二烯二酮 新 | 39025-23-5 |
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
|
![]() |
BCP33693 | Vonafexor 新 | 1192171-69-9 |
Vonafexor is a farnesoid X receptor agonist.
|
![]() |
BCP33226 | LY2562175 新 | 1103500-20-4 |
LY2562175 is a potent and selective FXR agonist with an EC50 of 193 nM.
|
![]() |
BCP21176 | 盐酸司维拉姆 新 | 152751-57-0 |
Sevelamer Hcl is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.
|
![]() |
BCP28929 | Nidufexor | 1773489-72-7 |
Nidufexor is a farnesoid X receptor (FXR) agonist.
|
![]() |
BCP29283 | Cilofexor | 1418274-28-8 |
Cilofexor is a farnesoid X receptor (FXR) agonist.
|
![]() |
BCP22751 | GW4064 新 | 278779-30-9 |
GW 4064 is a potent FXR agonist with EC50 of 65 nM.
|
![]() |
BCP19638 | BAR502 | 1612191-86-2 |
BAR502 is a dual FXR and GPBAR1 agonist with IC50 values of 2 μM and 0.4 μM, respectively.
|
