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CaSR

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CaSR

结构式 货号 产品名称 CAS号
Evocalcet 结构式
BCP33803 伊万卡赛 870964-67-3
Evocalcet is an orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon administration, evocalcet allosterically binds to and inhibits the activity of CaR, thereby suppressing the production of serum parathyroid hormone (PTH) and prevents the PTH-mediated efflux of calcium from bone and normalizes calcium levels.
Etelcalcetide HCl 结构式
BCP25093 维考西肽盐酸盐 1334237-71-6
Etelcalcetide, also known as AMG 416 and KAI-4169, is a D-amino peptide calcimimetic undergoing clinical evaluation for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis.
Ronacaleret HCl 结构式
BCP11469 Ronacaleret HCl 702686-96-2
Ronacaleret, also known as SB751689, is an orally-active calcium-sensing receptor (CaSR) antagonist that has the potential for therapeutic utility in the stimulation of PTH release, notably as a bone anabolic agent comparable to recombinant human PTH(1-34) (rhPTH(1-34)).
SB-423562 结构式
BCP29936 SB-423562 351490-27-2
SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist.
Strontium chloride 结构式
BCP28245 氯化锶 10025-70-4
Calcium sensing receptor (CaSR) agonist. Activates ERK1/2 signaling, intracellular calcium mobilization, and calcitonin secretion. Enhances osteogenic differentiation of mesenchymal stem cells.
Cinacalcet 结构式
BCP07181 甲状旁腺激素;西那卡塞 226256-56-0
AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism.
(S)-Cinacalcet hydrochloride 结构式
BCP12457 S-盐酸西那卡塞 1217809-88-5
Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
Ent-Cinacalcet Hydrochloride 结构式
BCP14361 S-西那卡塞 694495-47-1
Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
NPS-2143 hydrochloride 结构式
BCP16483 NPS-2143 hydrochloride 324523-20-8
NPS-2143(SB 262470A ) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.
Strontium ranelate 结构式
BCP02341 雷尼酸锶 135459-87-9
Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation.
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