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Pyruvate Kinase

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Pyruvate Kinase

结构式 货号 产品名称 CAS号
PKR-IN-C51 结构式
BCP34854 PKR-IN-C51 1314594-23-4
PKR-IN-C51 is a protein kinase R (PKR) inhibitor.
Mitapivat 结构式
BCP19727 Mitapivat 1260075-17-9
Mitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.
PKM2 inhibitor 结构式
BCP23555 PKM2 inhibitor 94164-88-2
PKM2 inhibitor is a pyruvate kinase M2 (PKM2) inhibitor with an IC50 of 2.95 μM.
DASA-58 结构式
BCP16322 DASA-58 1203494-49-8
DASA-58 is a selective activator of pyruvate kinase M2 (PKM2; AC50 = 38 nM in vitro, EC50 = 19.6 μM in cells).DASA-58 converts PKM2 to a constitutively active enzyme state that is resistant to inhibition by tyrosine-phosphorylated proteins.
Shikonin 结构式
BCP29329 紫草素 517-89-5
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin has shown various biological activities, including inhibition of TNF-α, NF-κB, HIV-1.
ML265 结构式
BCP12877 ML265 1221186-53-3
ML265 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and little or no activity versus PKM1, PKL and PKR.
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