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PI3K/Akt/mTOR

结构式 货号 产品名称 CAS号
Disitertide 结构式
BCP46789 地司特泰 272105-42-7
Disitertide is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide is also a PI3K inhibitor and an apoptosis inducer.
COH-SR4 结构式
BCP46777 COH-SR4 73439-19-7
COH-SR4 is a bonafide uncoupler that induces energetic stress on cells, consequently leading to AMPK activation and mTOR inhibition without any effects on ERK/MEK MAPK signaling.
Akt Inhibitor IV 结构式
BCP22722 AKT 蛋白激酶抑制剂IV 681281-88-9
Akt Inhibitor IV is n Inhibitor of Akt protein kinase
(E)-Akt inhibitor-IV 结构式
BCP46776 (E)-Akt inhibitor-IV 959841-49-7
(E)-Akt inhibitor-IV ((E)-AKTIV) is a PI3K-Akt inhibitor, with potent cytotoxic.
IHMT-PI3Kδ-372 结构式
BCP46775 IHMT-PI3Kδ-372 2429889-62-1
IHMT-PI3Kδ-372 is a potent and selective phosphatidylinositol 3-kinase δ (PI3Kδ) inhibitor with an IC50 of 14 nM in the biochemical assay.
BAY-3827 结构式
BCP46774 BAY-3827 2377576-35-5
BAY-3827 is a potent AMPK inhibitor which inhibits AMPK kinase activity with IC50 values of 1.4 nM at a low, 10 μM ATP concentration and 15 nM at a high, 2 mM ATP concentration.
RSVA 405 结构式
BCP46773 RSVA 405 140405-36-3
RSVA-405 is a potent STAT3 inhibitor and is an analog of resveratol.
WAY-119064 结构式
BCP46772 WAY-119064 1198098-03-1
WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.
A674563 HCl 结构式
BCP46680 A674563 HCl A674563HCl
A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively.
Camonsertib 结构式
BCP46512 Camonsertib 2417489-10-0
Camonsertib, also known as RP 3500, is aA Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors.
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