Ralinepag
| CAS号 | 1187856-49-0 | 货号 | BCP30843 |
| 中文名 | Ralinepag | ||
| 英文名 | Ralinepag | ||
| 中文别名 | |||
| 英文别名 | APD-811; APD 811; APD811; | ||
| 分子式 | C23H26ClNO5 | 分子量 | 431.91 |
| 生物活性 | Ralinepag, also known as APD-811, is an orally available agonist of the prostacyclin (IP) receptor, is an investigational drug candidate internally discovered and developed by Arena and intended for the treatment of vasospastic diseases, such as Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, which elicits a potent vasodilation and inhibition of platelet aggregation when binding to this receptor. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Prostaglandin Receptor | ||
结构式
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