Derenofylline
| CAS号 | 251945-92-3 | 货号 | BCP32768 |
| 中文名 | Derenofylline | ||
| 英文名 | Derenofylline | ||
| 中文别名 | |||
| 英文别名 | SLV-320; SLV 320; SLV 320; | ||
| 分子式 | C18H20N4O | 分子量 | 308.38 |
| 生物活性 | Derenofylline, also known as SLV320, is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM) with a selectivity factor of at least 200 versus other adenosine receptor subtypes. SLV320 significantly decreased albuminuria by about 50%, but did not alter glomerular filtration rate (GFR). SLV320 prevented nephrectomy-dependent rise in plasma levels of creatinine kinase (CK), ALT and AST. SLV320 suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats with 5/6 nephrectomy. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Adenosine Receptor | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！