TC-I 2000

  • Chemical Properties
CAS No. 1159996-20-9 Cat. No. BCP33074
Name TC-I 2000
Synonyms TC I 2000; TCI 2000; TCI2000;
Formula C23H18F4N2O M. Wt 414.4
  • Biological Activity
Description TC-I 2000 is a potent and orally bioactive TRPM8 channel blocker. TC-I 2000 was shown to inhibit icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells (IC50 = 53 nM).
Pathways Ion Channel/Membrane Transporter 
Targets TRP Channel 

Structure

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