Vandetanib trifluoroacetate
| CAS No. | 338992-53-3 | Cat. No. | BCP33121 |
| Name | Vandetanib trifluoroacetate | ||
| Synonyms | Zactima trifluoroacetate;ZD6474 trifluoroacetate;ZD-6474 trifluoroacetate;ZD 6474 trifluoroacetate; | ||
| Formula | C24H25BrF4N4O4 | M. Wt | 589.38 |
| Description | Vandetanib trifluoroacetate is a potent inhibitor of VEGFR2 with IC50 of 40 nM.Vandetanib is an anti-cancer drug that is used for the treatment of certain tumours of thethyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VEGFR | ||
Structure
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