LC3-mHTT-IN-AN1
| CAS No. | 486443-73-6 | Cat. No. | BCP33879 |
| Name | LC3-mHTT-IN-AN1 | ||
| Synonyms | |||
| Formula | C15H9Br2NO3 | M. Wt | 411.04 |
| Description | LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons. | ||
| Pathways | Others Pathway | ||
| Targets | Autophagy | ||
Structure
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