Acriflavine hydrochloride

  • Chemical Properties
CAS No. 8063-24-9 Cat. No. BCP34400
Name Acriflavine hydrochloride
Synonyms Acriflavine HCl;
Formula C27H28Cl4N6 M. Wt 578.36
  • Biological Activity
Description Acriflavine Hydrochloride is an inhibitor of HIF-1α. It acts by inducing cell death and apoptosis in several glioma cell lines, targeting HIF-1α-mediated pathways, and decreasing the level of PGK1, VEGF and HIF-1α in vitro and in vivo.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets HIF 

Structure

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