恩他卡朋钠盐
| CAS号 | 1047659-02-8 | 货号 | BCP37301 |
| 中文名 | 恩他卡朋钠盐 | ||
| 英文名 | Entacapone sodium salt | ||
| 中文别名 | |||
| 英文别名 | |||
| 分子式 | C14H14N3NaO5 | 分子量 | 327.27 |
| 生物活性 | Entacapone sodium salt is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone sodium salt inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone sodium salt is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone sodium salt can be used for the research of Parkinson's disease. Entacapone sodium salt serves as a inhibits FTO demethylation activity with an IC50 of 3.5 μM and can be used for the research of metabolic disorders. | ||
| 信号通路 | Protease/Metabolic Enzyme Neuro Signaling Pathway | ||
| 靶 点 | COMT | ||
结构式
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