Ro 20-1724
| CAS No. | 29925-17-5 | Cat. No. | BCP42971 |
| Name | Ro 20-1724 | ||
| Synonyms | Ro20-1724 ; Ro-20-1724; | ||
| Formula | C15H22N2O3 | M. Wt | 278.35 |
| Description | Ro 20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase, selective for PDE4 (IC50 = 2.0 μM). It weakly inhibits PDE3 with a Ki value greater than 25 µM. Ro 20-1724 inhibits the release of cytokines and other inflammatory signals as well as prevents the development of reactive oxygen species. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Phosphodiesterase/PDE | ||
Structure
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