LQZ-7I
  • 化学数据
CAS号 195822-23-2 货号 BCP43515
中文名 LQZ-7I
英文名 LQZ-7I
中文别名
英文别名 LQZ 7I; LQZ7I;
分子式 C20H14F2N4 分子量 348.35
  • 用途
生物活性 LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly.
信号通路 Apoptosis Pathway 
靶 点 Survivin 

结构式

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