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CAS号 | 195822-23-2 | 货号 | BCP43515 |
中文名 | LQZ-7I | ||
英文名 | LQZ-7I | ||
中文别名 | |||
英文别名 | LQZ 7I; LQZ7I; | ||
SMILES | C1=CC=C2C(=C1)N=C(C(=N2)NC3=CC=C(C=C3)F)NC4=CC=C(C=C4)F | ||
化学名称 | |||
分子式 | C20H14F2N4 | 分子量 | 348.35 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly. |
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