PF-06446846 hydrochloride
| CAS No. | 1632250-50-0 | Cat. No. | BCP43977 |
| Name | PF-06446846 hydrochloride | ||
| Synonyms | PF-06446846 HCl; PF 06446846 HCl; PF06446846 HCl; | ||
| Formula | C22H21Cl2N7O | M. Wt | 470.36 |
| Description | PF-06446846 is a selective orally active PCSK9 inhibitor that appears to act by causing the ribosome to stall when synthesizing PCSK9. PCSK9 binds to the LDL receptor, preventing it from removing LDL cholesterol from the blood. PF-06446846 was found to reduce plasma PCSK9 and total cholesterol levels in rats. | ||
| Related Products | 1632250-49-7（PF-06446846） | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Serine Protease | ||
Structure
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