苯肼硫酸盐
| CAS号 | 156-51-4 | 货号 | BCP44466 |
| 中文名 | 苯肼硫酸盐 | ||
| 英文名 | Phenelzine Sulfate | ||
| 中文别名 | 硫酸苯乙肼; | ||
| 英文别名 | |||
| 分子式 | C8H14N2O4S | 分子量 | 234.27 |
| 生物活性 | Phenelzine Sulfate is a hydrazine derivative and a potent non-selective monoamine oxidase (MAO) inhibitor with anxiolytic and antidepressant properties. Phenelzine sulfate irreversibly binds to MAO, thereby blocking the oxidative deamination of monoamines resulting in an increased concentration of biogenic amines and a concurrent decrease in catabolism of monoamine neurotransmitters, norepinephrine and serotonin, in the brain. In addition, through its primary metabolite phenylethylidenehyrazine (PEH), phenelzine causes elevated GABA levels in the caudate-putamen and nucleus accumbens thereby exerting its anxiolytic effects. | ||
| 信号通路 | Neuro Signaling Pathway | ||
| 靶 点 | Monoamine Oxidase | ||
结构式
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