帕替麦布硫酸盐
| CAS号 | 608510-47-0 | 货号 | BCP45168 |
| 中文名 | 帕替麦布硫酸盐 | ||
| 英文名 | Pactimibe sulfate | ||
| 中文别名 | |||
| 英文别名 | CS-505 sulfate; CS505 sulfate; CS 505 sulfate; | ||
| 分子式 | C50H82N4O10S | 分子量 | 931.28 |
| 生物活性 | Pactimibe, also known as CS-505, is a ACAT inhibitor. Pactimibe stabilizes atherosclerotic plaque through macrophage acyl-CoA:cholesterol acyltransferase inhibition in WHHL rabbits. Pactimibe reduces and stabilizes atherosclerotic lesions by cholesterol-lowering and direct effects in apolipoprotein E-deficient mice. Pactimibe inhibits cholesterol absorption from the intestine, reduces cholesteryl ester formation in the liver, and enhances its elimination from the body. The Triton WR-1339 experiment showed that pactimibe inhibited secretion of very low density lipoprotein cholesterol from the liver. These results suggest that pactimibe is likely to have multiple mechanisms of action responsible for its effectiveness in reducing serum cholesterol. | ||
| 上下游产品 | 189198-30-9（帕替麦布） | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！