
帕替麦布硫酸盐 新

规格 | 价格(CNY) | 是否现货 | 购买咨询 |
---|---|---|---|
10.00 mg | ¥3500.00 | In-stock | 购买咨询 |
25.00 mg | ¥5800.00 | In-stock | 购买咨询 |
50.00 mg | ¥7500.00 | In-stock | 购买咨询 |
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CAS号 | 608510-47-0 | 货号 | BCP45168 |
关联产品 | 189198-30-9(帕替麦布) | ||
中文名 | 帕替麦布硫酸盐 | ||
英文名 | Pactimibe sulfate | ||
中文别名 | |||
英文别名 | CS-505 sulfate; CS505 sulfate; CS 505 sulfate; | ||
SMILES | CCCCCCCCN1CCC2=C(C(=C(C(=C21)NC(=O)C(C)(C)C)C)CC(=O)O)C.CCCCCCCCN1CCC2=C(C(=C(C(=C21)NC(=O)C(C)(C)C)C)CC(=O)O)C.OS(=O)(=O)O | ||
化学名称 | |||
分子式 | C50H82N4O10S | 分子量 | 931.28 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Pactimibe, also known as CS-505, is a ACAT inhibitor. Pactimibe stabilizes atherosclerotic plaque through macrophage acyl-CoA:cholesterol acyltransferase inhibition in WHHL rabbits. Pactimibe reduces and stabilizes atherosclerotic lesions by cholesterol-lowering and direct effects in apolipoprotein E-deficient mice. Pactimibe inhibits cholesterol absorption from the intestine, reduces cholesteryl ester formation in the liver, and enhances its elimination from the body. The Triton WR-1339 experiment showed that pactimibe inhibited secretion of very low density lipoprotein cholesterol from the liver. These results suggest that pactimibe is likely to have multiple mechanisms of action responsible for its effectiveness in reducing serum cholesterol. |
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