Adenosine 5'-(α,β-methylene)diphosphate sodium salt

  • Chemical Properties
CAS No. 89016-30-8 Cat. No. BCP45815
Name Adenosine 5'-(α,β-methylene)diphosphate sodium salt
Synonyms MethADP sodium salt;α,β-Methyleneadenosine 5'-diphosphate monosodium salt;
Formula C11H18N5NaO9P2 M. Wt 449.23
  • Biological Activity
Description Adenosine 5'-(α,β-methylene)diphosphate sodium salt is an Ecto-5'-nucleotidase/CD73 inhibitor. Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells (MCF7/A6 and L1210/A). Also increases rhodamine uptake and inhibits rhodamine efflux from ecto-5'-nucleotidase-positive MDR cells. Vasoconstrictor.
Pathways Others Pathway 
Targets Others 

Structure

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