Adenosine 5'-(α,β-methylene)diphosphate sodium salt New
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| CAS No. | 89016-30-8 | Cat. No. | BCP45815 |
| Name | Adenosine 5'-(α,β-methylene)diphosphate sodium salt | ||
| Synonyms | MethADP sodium salt;α,β-Methyleneadenosine 5'-diphosphate monosodium salt; | ||
| SMILES | C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(CP(=O)(O)[O-])O)O)O)N.[Na+] | ||
| Chemical Name | |||
| Formula | C11H18N5NaO9P2 | M. Wt | 449.23 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Adenosine 5'-(α,β-methylene)diphosphate sodium salt is an Ecto-5'-nucleotidase/CD73 inhibitor. Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells (MCF7/A6 and L1210/A). Also increases rhodamine uptake and inhibits rhodamine efflux from ecto-5'-nucleotidase-positive MDR cells. Vasoconstrictor. | ||
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