西达尿苷
| CAS号 | 1141397-80-9 | 货号 | BCP46046 |
| 中文名 | 西达尿苷 | ||
| 英文名 | Cedazuridine | ||
| 中文别名 | |||
| 英文别名 | E7727; E-7727; E 7727; WHO 10741; WHO-10741; WHO10741; | ||
| 分子式 | C9H14F2N2O5 | 分子量 | 268.21 |
| 生物活性 | Cedazuridine is an orally available synthetic nucleoside analog derived from tetrahydrouridine (THU) and cytidine deaminase inhibitor (CDAi), that can potentially be used to prevent the breakdown of cytidines. Upon oral administration, cedazuridine binds to and inhibits CDA, an enzyme primarily found in the gastrointestinal (GI) tract and liver that catalyzes the deamination of cytidine and cytidine analogs. Given in combination with a cytidine, such as the antineoplastic hypomethylating agent decitabine, it specifically prevents its breakdown and increases its bioavailability and efficacy. In addition, this allows for lower doses of decitabine to be administered, which results in decreased decitabine-associated GI toxicity. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Others | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！