西达尿苷新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP46046CAS号：1141397-80-9纯度：98%

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CAS号	1141397-80-9	货号	BCP46046
中文名	西达尿苷
英文名	Cedazuridine
中文别名
英文别名	E7727; E-7727; E 7727; WHO 10741; WHO-10741; WHO10741;
SMILES	C1CN(C(=O)NC1O)C2C(C(C(O2)CO)O)(F)F
化学名称
分子式	C9H14F2N2O5	分子量	268.21
纯度	98%	配送	惯例下常温包邮
产品描述	Cedazuridine is an orally available synthetic nucleoside analog derived from tetrahydrouridine (THU) and cytidine deaminase inhibitor (CDAi), that can potentially be used to prevent the breakdown of cytidines. Upon oral administration, cedazuridine binds to and inhibits CDA, an enzyme primarily found in the gastrointestinal (GI) tract and liver that catalyzes the deamination of cytidine and cytidine analogs. Given in combination with a cytidine, such as the antineoplastic hypomethylating agent decitabine, it specifically prevents its breakdown and increases its bioavailability and efficacy. In addition, this allows for lower doses of decitabine to be administered, which results in decreased decitabine-associated GI toxicity.

西达尿苷 新