PI-273

  • Chemical Properties
CAS No. 925069-34-7 Cat. No. BCP46433
Name PI-273
Synonyms PI273; PI 273;
Formula C16H16ClN3O2S2 M. Wt 381.9
  • Biological Activity
Description PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis.
Pathways PI3K/Akt/mTOR 
Targets PI4K 

Structure

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