PHD-1-IN-1
| CAS No. | 2009343-14-8 | Cat. No. | BCP47256 |
| Name | PHD-1-IN-1 | ||
| Synonyms | |||
| Formula | C13H8N4 | M. Wt | 220.23 |
| Description | PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | HIF | ||
Structure
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