MCT4-IN-1

  • Chemical Properties
CAS No. 2445185-57-7 Cat. No. BCP47800
Name MCT4-IN-1
Synonyms
Formula C26H20ClN3O6S M. Wt 537.97
  • Biological Activity
Description MCT4-IN-1 is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC50 of 77 nM and a Ki of 11 nM. MCT4-IN-1 targets to the cytosolic domain of MCT4. MCT4-IN-1 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MCT4-IN-1 has the potential for MCT4 transporter inhibition research.
Pathways Ion Channel/Membrane Transporter 

Structure

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