tri-GalNAc COOH
| CAS No. | 1953146-81-0 | Cat. No. | BCP48074 |
| Name | tri-GalNAc COOH | ||
| Synonyms | SGN-46810; | ||
| Formula | C75H134N10O35 | M. Wt | 1735.93 |
| Description | Tri-GalNAc COOH is a functionalized asialoglycoprotein receptor ligand for lysosomal targeting chimera (LYTAC) research and development; incorporates an asialoglycoprotein receptor (ASGPR) ligand with PEG linker and carboxylic acid group reactive handle ready for conjugation to a target protein ligand. Upon binding to the ASGPR tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. Tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to liver hepatocytes. | ||
| Pathways | Others Pathway | ||
| Targets | PROTAC | ||
Structure
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