LOE 908 hydrochloride

  • Chemical Properties
CAS No. 143482-60-4 Cat. No. BCP48545
Name LOE 908 hydrochloride
Synonyms LOE 908 HCl;LOE-908 HCl;LOE908 HCl;
Formula C41H49ClN2O9 M. Wt 749.3
  • Biological Activity
Description LOE 908 hydrochloride is a broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na+ and K+ channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.
Pathways Ion Channel/Membrane Transporter 

Structure

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