eCF506
| CAS号 | 1914078-41-3 | 货号 | BCP49715 |
| 中文名 | eCF506 | ||
| 英文名 | eCF506 | ||
| 中文别名 | |||
| 英文别名 | derivative 11a;NXP-900; | ||
| 分子式 | C26H38N8O3 | 分子量 | 510.63 |
| 生物活性 | eCF506 is a potent and highl selective inhibitor towards Src tyrosine kinase with a 1000-fold selectivity over ABL. eCF506 inhibits SRC at subnanomolar concentration (IC50 < 0.5 nM). It is said that eCF506 is the first drug candidate of a second generation of Src inhibitors that will not only help to understand the complexity of some cancers but also the development of safer combination therapies. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | Src/Bcr Abl | ||
结构式
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