地加瑞克
| CAS号 | 214766-78-6 | 货号 | BCP20973 |
| 中文名 | 地加瑞克 | ||
| 英文名 | Degarelix | ||
| 中文别名 | |||
| 英文别名 | FE200486; FE-200486; FE 200486; ASP3550; ASP-3550; ASP 3550; | ||
| 分子式 | C82H103ClN18O16 | 分子量 | 1632.28 |
| 生物活性 | Degarelix, also known as FE-200486 and ASP-3550, is a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes. Degarelix acetate was approved in 2008. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | GnRH Receptor | ||
结构式
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