GNF5837

  • Chemical Properties
CAS No. 1033769-28-6 Cat. No. BCP07226
Name GNF5837
Synonyms GNF5837; GNF 5837;
Formula C28H21F4N5O2 M. Wt 535.49
  • Biological Activity
Description GNF-5837 is a potent pan-Trk inhibitor which display antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively).
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Trk Receptor 

Structure

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