Bay 11-7821
| CAS号 | 19542-67-7 | 货号 | BCP06798 |
| 中文名 | Bay 11-7821 | ||
| 英文名 | Bay 11-7821 | ||
| 中文别名 | |||
| 英文别名 | BAY11-7082; BAY-11-7082; BAY 117082; BAY117082; BAY-11708; | ||
| 分子式 | C10H9NO2S | 分子量 | 207.25 |
| 生物活性 | BAY 11-7082 is an inhibitor of κB kinase (IKK) that has pharmacological activities that include anticancer, neuroprotective, and anti-inflammatory effects. BAY 11-7082 strongly suppressed the production of nitric oxide, prostaglandin E(2), and tumor necrosis factor-α and reduced the translocation of p65, major subunit of nuclear factor-κB, and its upstream signaling events such as phosphorylation of IκBα, IKK, and Akt. In addition. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors. | ||
| 信号通路 | NFκB | ||
| 靶 点 | IκB/IKK | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！