JNJ-38158471
| CAS No. | 951151-97-6 | Cat. No. | BCP21621 |
| Name | JNJ-38158471 | ||
| Synonyms | JNJ38158471;JNJ 38158471; | ||
| Formula | C15H17ClN6O3 | M. Wt | 364.79 |
| Description | JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50=40nM. It also inhibits closely related tyrosine kinases, Ret (180nM) and Kit (500nM). It has no significant activity (>1 microM) against VEGFR-1 and VEGF | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VEGFR | ||
Structure
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