扎鲁司特
| CAS号 | 107753-78-6 | 货号 | BCP05226 |
| 中文名 | 扎鲁司特 | ||
| 英文名 | Zafirlukast | ||
| 中文别名 | |||
| 英文别名 | Accolate;ICI204219;ICI-204219;ICI 204219; | ||
| 分子式 | C31H33N3O6S | 分子量 | 575.68 |
| 生物活性 | Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily. Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Leukotriene Receptor | ||
结构式
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