Telmisartan

  • Chemical Properties
CAS No. 144701-48-4 Cat. No. BCP04513
Name Telmisartan
Synonyms TU-199;TU 199;TU199;
Formula C33H30N4O2 M. Wt 514.63
  • Biological Activity
Description Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Pathways GPCR/G Protein 
Targets Angiotensin Receptor 

Structure

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