替米沙坦
| CAS号 | 144701-48-4 | 货号 | BCP04513 |
| 中文名 | 替米沙坦 | ||
| 英文名 | Telmisartan | ||
| 中文别名 | |||
| 英文别名 | TU-199;TU 199;TU199; | ||
| 分子式 | C33H30N4O2 | 分子量 | 514.63 |
| 生物活性 | Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Angiotensin Receptor | ||
结构式
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