Etravirine

  • Chemical Properties
CAS No. 269055-15-4 Cat. No. BCP03562
Name Etravirine
Synonyms TMC-125;TMC 125;TMC125;
Formula C20H15BrN6O M. Wt 435.28
  • Biological Activity
Description Etravirine (TMC125), is highly active against wild-type HIV-1 with EC50 of 1.4 nM to 4.8 nM and shows some activity against HIV-2 with EC50 of 3.5 μM. TMC125 also inhibits a series of HIV-1 group M subtypes and circulating recombinant forms and a group O virus.
Pathways Microbiology/Virology 
Targets Reverse Transcriptase HIV 

Structure

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