Evodiamine
| CAS No. | 518-17-2 | Cat. No. | BCP02282 |
| Name | Evodiamine | ||
| Synonyms | Isoevodiamine; | ||
| Formula | C19H17N3O | M. Wt | 303.36 |
| Description | Evodiamine (Isoevodiamine), an alkaloid extract from Evodiae Fructus exhibits antitumor activities against the human tumor cells. Evodiamine induces the substantial amount of apoptosis both in Bcl-2- and Akt-overexpressing U937 cells but not in human peripheral blood mononuclear cells via caspase-independent apoptotic pathways.Evodiamine Evodiamine also inhibits tumor necrosis factor (TNF)-induced NF-kappaB and Akt activation but it has no effect on JNK or p38 MAPK activation.In addition, Evodiamine is an human topoisomerase I inhibitor. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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