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Evodiamine Chemical Structure

Evodiamine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02282CAS No. :518-17-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 518-17-2 Cat. No. BCP02282
Name Evodiamine
Synonyms Isoevodiamine;
SMILES
Chemical Name
Formula C19H17N3O M. Wt 303.36
Purity 98% Storage Store at 4-8°C
Description Evodiamine (Isoevodiamine), an alkaloid extract from Evodiae Fructus exhibits antitumor activities against the human tumor cells. Evodiamine induces the substantial amount of apoptosis both in Bcl-2- and Akt-overexpressing U937 cells but not in human peripheral blood mononuclear cells via caspase-independent apoptotic pathways.Evodiamine Evodiamine also inhibits tumor necrosis factor (TNF)-induced NF-kappaB and Akt activation but it has no effect on JNK or p38 MAPK activation.In addition, Evodiamine is an human topoisomerase I inhibitor.
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