JNK-IN-7
| CAS号 | 1408064-71-0 | 货号 | BCP13495 |
| 中文名 | JNK-IN-7 | ||
| 英文名 | JNK-IN-7 | ||
| 中文别名 | |||
| 英文别名 | JNK inhibitor; | ||
| 分子式 | C28H27N7O2 | 分子量 | 493.56 |
| 生物活性 | Covalent modification of IRAK1 by JNK-IN-7 is a possibility and subsequent biochemical kinase assay revealed anIC50 of ~10 nM against IRAK1. JNK-IN-7 exhibited binding inhibition of 95% or more to approximately 14 kinases at the concentration of 1.0 μM. JNK-IN-7 was next tested for its ability to inhibit the enzymatic activity of a panel of 121 kinases at a concentration of 1.0 μM . | ||
| 信号通路 | MAPK Pathway | ||
| 靶 点 | JNK | ||
结构式
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