PD90780

  • Chemical Properties
CAS No. 77422-99-2 Cat. No. BCP16228
Name PD90780
Synonyms PD-90780;PD 90780;
Formula C19H14N4O4 M. Wt 362.34
  • Biological Activity
Description PD90780 is a nonpeptide inhibitor of NGF binding to p75NTR (IC50 ~ 1 μM in CHO cells); binds NGF, not p75NTR. Affinity maybe altered by the presence of TrkA receptors. Neuroprotective.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Trk Receptor 

Structure

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