PD 123319 ditrifluoroacetate

  • Chemical Properties
CAS No. 136676-91-0 Cat. No. BCP16338
Name PD 123319 ditrifluoroacetate
Synonyms PD-123319 TFA; PD123319 ditrifluoroacetate; PD-123319 ditrifluoroacetate; PD123319 TFA salt;
Formula C35H36F6N4O8 M. Wt 754.67
  • Biological Activity
Description PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.PD-123319 is a selective, nonpeptide AT2R antagonist (IC50 = 5.6 nM vs. 100 nM for AT1R). PD-123319 has been used to selectively examine the specific roles for AT1R and AT2R in hypertensive and other vascular research-related models.
Pathways GPCR/G Protein 
Targets Angiotensin Receptor 

Structure

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