Valbenazine
| CAS号 | 1025504-45-3 | 货号 | BCP19498 |
| 中文名 | Valbenazine | ||
| 英文名 | Valbenazine | ||
| 中文别名 | |||
| 英文别名 | NBI 98854;NBI-98854;NBI98854; MT-5199; MT 5199; MT5199; | ||
| 分子式 | C24H38N2O4 | 分子量 | 418.57 |
| 生物活性 | Valbenazine, also known as NBI-98854 and MT-5199, is a potent and selective VMAT2 inhibitor. NBI-98854 is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. NBI-98854 is promising agent for the treatment of tardive dyskinesia.NBI-98854 significantly improved tardive dyskinesia and was well tolerated in patients. These results support the phase 3 clinical trials of NBI-98854 now underway. | ||
| 信号通路 | Ion Channel/Membrane Transporter | ||
| 靶 点 | Monoamine Transporter | ||
结构式
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