TG4-155

  • Chemical Properties
CAS No. 1164462-05-8 Cat. No. BCP25837
Name TG4-155
Synonyms TG-4-155; TG 4-155; TG4155; TG-4155; TG 4155;
Formula C23H26N2O4 M. Wt 394.47
  • Biological Activity
Description TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1. TG4-155 has an EP2 Schild KB of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor.
Pathways GPCR/G Protein 
Targets Prostaglandin Receptor 

Structure

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