Siramesine

  • Chemical Properties
CAS No. 147817-50-3 Cat. No. BCP08745
Name Siramesine
Synonyms Lu-28-179; Lu 28-179; Lu28-179; Lu-28179; Lu 28179; Lu28179;
Formula C30H31FN2O M. Wt 454.58
  • Biological Activity
Description Siramesine, also known as Lu-28-179, is a potent sigma-2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress.
Related Products 224177-60-0(Siramesine hydrochloride)
Pathways GPCR/G Protein 
Targets Sigma Receptor 

Structure

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
Service & Tech Support:orders@biochempartner.com
Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.