Siramesine hydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 224177-60-0 | Cat. No. | BCP27822 |
| Related Products | 147817-50-3（Siramesine） | ||
| Name | Siramesine hydrochloride | ||
| Synonyms | Siramesine HCl; Lu 28-179;Lu-28-179;Lu 28-179 hydrochloride; | ||
| SMILES | FC1=CC=C(N2C=C(CCCCN3CCC4(CC3)OCC5=CC=CC=C45)C6=C2C=CC=C6)C=C1.[H]Cl | ||
| Chemical Name | |||
| Formula | C30H32ClFN2O | M. Wt | 491.04 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Siramesine, also known as Lu-28-179, is a potent sigma-2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress. | ||
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