Siramesine hydrochloride
| CAS No. | 224177-60-0 | Cat. No. | BCP27822 |
| Name | Siramesine hydrochloride | ||
| Synonyms | Siramesine HCl; Lu 28-179;Lu-28-179;Lu 28-179 hydrochloride; | ||
| Formula | C30H32ClFN2O | M. Wt | 491.04 |
| Description | Siramesine, also known as Lu-28-179, is a potent sigma-2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress. | ||
| Related Products | 147817-50-3（Siramesine） | ||
| Pathways | GPCR/G Protein | ||
| Targets | Sigma Receptor | ||
Structure
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