BD1063 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 150208-28-9 | Cat. No. | BCP28878 |
| Name | BD1063 | ||
| Synonyms | BD 1063; BD-1063;206996-13-6(2HCl);BD-1063 Dihydrochloride; BD1063 Dihydrochloride;BD 1063 2HCl; | ||
| SMILES | CN1CCN(CCC2=CC=C(Cl)C(Cl)=C2)CC1 | ||
| Chemical Name | |||
| Formula | C13H18Cl2N2 | M. Wt | 273.20 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BD1063 is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor. Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine. In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism. | ||
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