Blarcamesine hydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 195615-84-0 | Cat. No. | BCP24794 |
| Name | Blarcamesine hydrochloride | ||
| Synonyms | AVex-73 hydrochloride;Anavex-2-73 HCl;Anavex 2-73; Anavex2-73; Anavex 2-73; Anavex-273; Anavex273; Anavex 273; AE-37 hydrochloride; | ||
| SMILES | CN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3.Cl | ||
| Chemical Name | |||
| Formula | C19H24ClNO | M. Wt | 317.85 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated the scopolamine- and dizocilpine-induced learning impairments. ANAVEX2-73 (300 µg/kg) also reversed the learning deficits in mice injected with Aβ(25-35) peptide, a non-transgenic Alzheimer's disease model. The neuroprotective activity of ANAVEX2-73, its mixed cholinergic/σ(1) activity, its low active dose range and its long duration of action together reinforce its therapeutic potential in Alzheimer's disease. | ||
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