RO-1138452

  • Chemical Properties
CAS No. 221529-58-4 Cat. No. BCP26234
Name RO-1138452
Synonyms RO1138452; RO 1138452;CAY10441;CAY 10441;CAY-10441;
Formula C19H23N3O M. Wt 309.41
  • Biological Activity
Description RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pKi is 9.3±0.1; in a recombinant IP receptor system, pKi is 8.7±0.06.
Pathways GPCR/G Protein 
Targets Prostaglandin Receptor 

Structure

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